Document Detail

Aluminium studies in dialysis encephalopathy.
MedLine Citation:
PMID:  740662     Owner:  NLM     Status:  MEDLINE    
The dialysis encephalopathy syndrome has a geographical distribution related to the aluminium content of the dialysis water supply. There is a close relationship between concentrations of water aluminium and serum aluminium, and patients with dialysis encephalopathy have serum aluminium concentrations greater than 400 microgram/litre. High serum aluminium is also associated with osteomalacic bone disease, and worsening anaemia. In dialysis encephalopathy, elevated concentrations of aluminium are found in CSF and in grey matter, and an aluminium burden of 2-8 g is calculated from whole body in vivo analysis. There is sufficient evidence for an aluminium toxicity syndrome to warrant specific removal of aluminium by water purification systems.
H L Elliott; A I Macdougall
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association     Volume:  15     ISSN:  0071-2736     ISO Abbreviation:  Proc Eur Dial Transplant Assoc     Publication Date:  1978  
Date Detail:
Created Date:  1979-04-25     Completed Date:  1979-04-25     Revised Date:  2008-02-21    
Medline Journal Info:
Nlm Unique ID:  0355210     Medline TA:  Proc Eur Dial Transplant Assoc     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  157-63     Citation Subset:  IM    
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MeSH Terms
Aluminum / analysis*,  blood
Body Burden
Brain Chemistry
Brain Diseases / blood,  etiology*
Renal Dialysis / adverse effects*
Water / analysis
Water Supply
Reg. No./Substance:
7429-90-5/Aluminum; 7732-18-5/Water

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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