| Aluminium hydroxide in bile-salt diarrhoea. | |
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MedLine Citation:
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PMID: 72956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The treatment of choleraic diarrhoea remains a problem. Cholestyramine is effective but long-term treatment is often impracticable. In-vitro studies have shown that aluminium hydroxide has bile-acid-binding properties comparable with those of cholestyramine. The bile-acid-binding properties of aluminium hydroxide have now been investigated in vivo and applied to the treatment of patients with choleraic diarrhoea. Aluminium hydroxide increased the faecal bile-salt concentration of patients with a normal bowel habit whereas magnesium hydroxide had no effect. Eight patients with severe choleraic diarrhoea were treated with aluminium-hydroxide suspension: bowel motion became less frequent and daily faecal weight fell. |
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Authors:
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A Sali; W R Murray; C MacKay |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1977 Nov |
Date Detail:
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Created Date: 1978-01-27 Completed Date: 1978-01-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 1051-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aluminum Hydroxide / therapeutic use* Bile Acids and Salts / analysis, metabolism* Diarrhea / drug therapy*, etiology Drug Evaluation Duodenal Ulcer / drug therapy Feces / analysis Humans Magnesium Hydroxide / therapeutic use Male Middle Aged Suspensions |
| Chemical | |
Reg. No./Substance:
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0/Bile Acids and Salts; 0/Suspensions; 1309-42-8/Magnesium Hydroxide; 21645-51-2/Aluminum Hydroxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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