Document Detail

Alternatives to routine ultrasound for eligibility assessment prior to early termination of pregnancy with mifepristone-misoprostol.
MedLine Citation:
PMID:  21091926     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To test the feasibility and efficacy of an approach that foregoes the routine use of ultrasound for the determination of eligibility for medical termination of pregnancy.
DESIGN: Prospective trial.
SETTING: Ten termination of pregnancy clinics in the USA.
POPULATION: A total of 4484 women seeking termination of pregnancy with mifepristone-misoprostol.
METHODS: Women provided estimates of the date of their last menstrual period and underwent pelvic bimanual and ultrasound examinations. We compared estimates of gestational age using these three methods.
MAIN OUTCOME MEASURE: Proportion of women of ≤9 weeks' gestation by woman or provider estimate, but >9 weeks' gestation by ultrasound.
RESULTS: The reliance on women's report of their last menstrual period together with physical examination to determine their eligibility for termination of pregnancy with mifepristone-misoprostol would result in few women (63/4008 or 1.6%) accepted for treatment outside the current limits of standard mifepristone-misoprostol regimens used for early termination of pregnancy (i.e. ≤63 days' gestation on ultrasound).
CONCLUSIONS: Last menstrual period and physical examination alone, without the routine use of ultrasound, are highly effective for the determination of women's eligibility for early termination of pregnancy with mifepristone-misoprostol.
H Bracken; W Clark; E S Lichtenberg; S M Schweikert; J Tanenhaus; A Barajas; L Alpert; B Winikoff
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't     Date:  2010-11-23
Journal Detail:
Title:  BJOG : an international journal of obstetrics and gynaecology     Volume:  118     ISSN:  1471-0528     ISO Abbreviation:  BJOG     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-14     Completed Date:  2011-02-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100935741     Medline TA:  BJOG     Country:  England    
Other Details:
Languages:  eng     Pagination:  17-23     Citation Subset:  AIM; IM    
Copyright Information:
© 2010 The Authors Journal compilation © RCOG 2010 BJOG An International Journal of Obstetrics and Gynaecology.
Gynuity Health Projects, New York, NY 10010, USA.
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MeSH Terms
Abortifacient Agents, Nonsteroidal / administration & dosage*
Abortion, Induced / methods*
Drug Therapy, Combination
Feasibility Studies
Gestational Age
Mifepristone / administration & dosage*
Misoprostol / administration & dosage*
Physical Examination
Prospective Studies
Self Administration
Ultrasonography, Prenatal
Reg. No./Substance:
0/Abortifacient Agents, Nonsteroidal; 59122-46-2/Misoprostol; 84371-65-3/Mifepristone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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