| Alternatives to lung transplantation: treatment of pulmonary arterial hypertension. | |
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MedLine Citation:
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PMID: 21511098 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The development of targeted therapies for pulmonary arterial hypertension currently based on prostaglandin, nitric oxide, and endothelin pathways has resulted in major advances in the treatment of patients with pulmonary arterial hypertension. This article reviews the current evidence that supports both the use of mono- and combination therapy. The article also considers the role of atrial septostomy in the treatment of pulmonary arterial hypertension, particularly as a bridge to transplantation. Finally, the article provides a review of the role and outcomes of pulmonary thromboendartertectomy for patients with chronic thromboembolic pulmonary hypertension. |
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Authors:
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Paul A Corris |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Clinics in chest medicine Volume: 32 ISSN: 1557-8216 ISO Abbreviation: Clin. Chest Med. Publication Date: 2011 Jun |
Date Detail:
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Created Date: 2011-04-22 Completed Date: 2011-08-15 Revised Date: 2011-12-06 |
Medline Journal Info:
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Nlm Unique ID: 7907612 Medline TA: Clin Chest Med Country: United States |
Other Details:
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Languages: eng Pagination: 399-410 Citation Subset: IM |
Copyright Information:
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Copyright © 2011. Published by Elsevier Inc. |
Affiliation:
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Institute of Cellular Medicine, Newcastle University and Newcastle upon Tyne Hospitals NHS Foundation Trust, NE77DN, UK. Paul.corris@ncl.ac.uk |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Antihypertensive Agents
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therapeutic use Atrial Septum / surgery Endarterectomy Epoprostenol / analogs & derivatives, therapeutic use Humans Hypertension, Pulmonary* / drug therapy, mortality, surgery Phosphodiesterase 5 Inhibitors / therapeutic use Prognosis Receptors, Endothelin / antagonists & inhibitors |
| Chemical | |
Reg. No./Substance:
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0/Antihypertensive Agents; 0/Phosphodiesterase 5 Inhibitors; 0/Receptors, Endothelin; 35121-78-9/Epoprostenol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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