| Alternative therapies: what role do they have in the management of lupus? | |
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MedLine Citation:
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PMID: 20947552 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Systemic lupus erythematosus (SLE) is an autoimmune disease with higher morbidity and mortality among ethnic Chinese patients than Whites. Corticosteroid and other immunosuppressive drugs, including cyclophosphamide, azathioprine, and hydroxychloroquine are traditional therapies for this disease. Since the year 2000, mycophenolate mofetil and rituximab have been widely used in refractory SLE or severe lupus nephritis. Because the high disease activity remains, even after active therapy, and serious side effects from Western medicines may develop, more than 40% of SLE patients in Western countries are pursuing complementary and alternative therapies (CATs). CAT remedies are multiplex, and include herbal medicines, diets and vitamins, acupuncture, chiropractice, folk medicine, massage, spiritual healing, etc. Many herbal formulas have been used but in general their efficacy in treating lupus is doubted because of the lack of strong evidence. Tripterygium (T2) has demonstrated good efficacy in rheumatoid arthritis (RA) and SLE, but widespread use is limited due to the side effects. Through randomized clinical trials, we hope in the future that some Chinese medicines may be found helpful as CATs for SLE. |
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Authors:
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C-T Chou |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Lupus Volume: 19 ISSN: 1477-0962 ISO Abbreviation: Lupus Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-15 Completed Date: 2011-03-24 Revised Date: 2011-07-11 |
Medline Journal Info:
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Nlm Unique ID: 9204265 Medline TA: Lupus Country: England |
Other Details:
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Languages: eng Pagination: 1425-9 Citation Subset: IM |
Affiliation:
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Division of Allergy-Immunology-Rheumatology, Department of Medicine, Veterans General Hospital, Taipei, Taiwan. ctchou@vghtpe.gov.tw |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Asian Continental Ancestry Group Complementary Therapies / methods* Humans Lupus Erythematosus, Systemic / ethnology, therapy* Morbidity / trends World Health |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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