| Alternative pathway of complement in multiple myeloma. | |
| | |
MedLine Citation:
|
PMID: 6800254 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The alternative pathway of complement was studied in 16 newly diagnosed and 2 previously treated patients with multiple myeloma. Functional activity of this pathway was abnormal in 10 of these 18 patients (55%). These abnormalities correlated with depressed levels of alternative pathway components in 3 of 10 patients, but in the remaining 7, no etiology was demonstrated. There was an inverse correlation between activity and concentration of the monoclonal protein. This defect is an additional factor that may predispose patients with myeloma to overwhelming infection. |
| | |
Authors:
|
E H Kraut; A L Sagone |
Related Documents
:
|
1621434 - Igg-anticardiolipin-antibodies are markers for cerebral and peripheral artery disease. 2634754 - Cryoglobulin studies in systemic lupus erythematosus. 8379684 - Autoantibodies to cartilage collagens in relapsing polychondritis. 20673894 - Preserved splenic function after angioembolisation of high grade injury. 9843464 - Sustained ventricular arrhythmias in patients receiving thrombolytic therapy: incidence... 16464914 - The prognostic impact of coronary flow-reserve assessed by doppler echocardiography in ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: American journal of hematology Volume: 11 ISSN: 0361-8609 ISO Abbreviation: Am. J. Hematol. Publication Date: 1981 Dec |
Date Detail:
|
Created Date: 1982-04-22 Completed Date: 1982-04-22 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7610369 Medline TA: Am J Hematol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 335-45 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Complement Activation* Complement Pathway, Alternative* Complement System Proteins / analysis Humans Immunodiffusion Immunoelectrophoresis Immunoglobulins / analysis Multiple Myeloma / blood, immunology* |
| Chemical | |
Reg. No./Substance:
|
0/Immunoglobulins; 9007-36-7/Complement System Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Long-term efficacy of diltiazem in chronic stable angina associated with atherosclerosis: effect on ...
Next Document: Sterility and use patterns of multiple-dose vials.