| Alternative approaches to cervical cancer screening for developing countries. | |
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MedLine Citation:
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PMID: 22385539 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cervical cancer remains the most common cancer among women living in developing countries, largely because of the failure either to initiate or sustain effective cervical-cancer screening programmes. This potentially preventable and curable cancer continues to cause high mortality among relatively young women residing in low-resource countries. Cytology as a screening test, linked with a robust healthcare infrastructure, has significantly affected cervical cancer prevention in countries that have had sufficient resources to establish and sustain well-conducted programmes. The failure to establish such programmes has stimulated a large body of research into alternative screening tests and approaches to cervical-cancer prevention. Two of the most recent research methods have been visual inspection with acetic acid and molecular testing for high-risk types of human papillomavirus deoxyribonucleic acid. Visual inspection with acetic acid has shown a great deal of promise in cross-sectional studies; however, in randomised-controlled trials, it has been shown to be significantly less effective in reducing cervical cancer or its precursors. The development of point-of-care human papillomavirus or other highly sensitive tests for the prevention of cervical cancer is imperative. It has also been clearly shown that linking testing or screening to treatment (so-called 'screen and treat') without the intervention of colposcopy or the need for sophisticated laboratories may potentially prevent cervical cancer in large numbers of women. |
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Authors:
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Thomas C Wright; Louise Kuhn |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Best practice & research. Clinical obstetrics & gynaecology Volume: 26 ISSN: 1532-1932 ISO Abbreviation: Best Pract Res Clin Obstet Gynaecol Publication Date: 2012 Apr |
Date Detail:
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Created Date: 2012-03-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101121582 Medline TA: Best Pract Res Clin Obstet Gynaecol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 197-208 Citation Subset: IM |
Copyright Information:
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Copyright © 2011. Published by Elsevier Ltd. |
Affiliation:
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Department of Pathology, College of Physicians and Surgeons of Columbia University, Room 16-404, P&S Building, 630 W. 168th Street, New York, NY 10032, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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