Document Detail

Alternative Methods to Central Venous Pressure for Assessing Volume Status in Critically Ill Patients.
MedLine Citation:
PMID:  23089635     Owner:  NLM     Status:  Publisher    
INTRODUCTION: Early goal-directed therapy increases survival in persons with sepsis but requires placement of a central line. We evaluate alternative methods to measuring central venous pressure (CVP) to assess volume status, including peripheral venous pressure (PVP) and stroke volume variation (SVV), which may facilitate nurse-driven resuscitation protocols. METHODS: Patients were enrolled in the emergency department or ICU of an academic medical center. Measurements of CVP, PVP, SVV, shoulder and elbow position, and dichotomous variables Awake, Movement, and Vented were measured and recorded 7 times during a 1-hour period. Regression analysis was used to predict CVP from PVP and/or SVV, shoulder/elbow position, and dichotomous variables. RESULTS: Twenty patients were enrolled, of which 20 had PVP measurements and 11 also had SVV measurements. Multiple regression analysis demonstrated significant predictive relationships for CVP using PVP (CVP = 6.7701 + 0.2312 × PVP - 0.1288 × Shoulder + 12.127 × Movement - 4.4805 × Neck line), SVV (CVP = 14.578 - 0.3951 × SVV + 18.113 × Movement), and SVV and PVP (CVP = 4.2997 - 1.1675 × SVV + 0.3866 × PVP + 18.246 × Awake + 0.1467 × Shoulder = 0.4525 × Elbow + 15.472 × Foot line + 10.202 × Arm line). DISCUSSION: PVP and SVV are moderately good predictors of CVP. Combining PVP and SVV and adding variables related to body position, movement, ventilation, and sleep/wake state further improves the predictive value of the model. The models illustrate the importance of standardizing patient position, minimizing movement, and placing intravenous lines proximally in the upper extremity or neck.
Lisa Stoneking; Lawrence A Deluca; Albert B Fiorello; Brendan Munzer; Nicola Baker; Kurt R Denninghoff
Related Documents :
8911845 - Initial reperfusion with 2,3 butanedione monoxime is better than hyperkalemic reperfusi...
18008115 - Cardioprotective effect and mechanism of action of landiolol on the ischemic reperfused...
2396565 - Effects of neutrophil depletion and superoxide dismutase on postischemic hypoperfusion ...
15051645 - Metabolic and functional protection by selective inhibition of nitric oxide synthase 2 ...
19801905 - Site-dependent differences in collagen lamellae in the corneal substantia propria of be...
18551995 - Ventilation-perfusion distribution and shunt fraction during one-lung ventilation: effe...
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-19
Journal Detail:
Title:  Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association     Volume:  -     ISSN:  1527-2966     ISO Abbreviation:  J Emerg Nurs     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7605913     Medline TA:  J Emerg Nurs     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Emergency Nurses Association. Published by Mosby, Inc. All rights reserved.
Tucson, AZ.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Glucocorticoid receptor dimerization is required for proper recovery of LPS-induced inflammation, si...
Next Document:  Production of nitric oxide is lower in shiga toxin-stimulated neutrophils of infants compared to tho...