| Alternative Candida albicans lifestyles: growth on surfaces. | |
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MedLine Citation:
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PMID: 16153165 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Candida albicans, an opportunistic fungal pathogen, causes a wide variety of human diseases such as oral thrush and disseminated candidiasis. Many aspects of C. albicans physiology have been studied during liquid growth, but in its natural environment, the gastrointestinal tract of a mammalian host, the organism associates with surfaces. Growth on a surface triggers several behaviors, such as biofilm formation, invasion, and thigmotropism, that are important for infection. Recent discoveries have identified factors that regulate these behaviors and revealed the importance of these behaviors for pathogenesis. |
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Authors:
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Carol A Kumamoto; Marcelo D Vinces |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Annual review of microbiology Volume: 59 ISSN: 0066-4227 ISO Abbreviation: Annu. Rev. Microbiol. Publication Date: 2005 |
Date Detail:
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Created Date: 2005-09-12 Completed Date: 2006-01-06 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0372370 Medline TA: Annu Rev Microbiol Country: United States |
Other Details:
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Languages: eng Pagination: 113-33 Citation Subset: IM |
Affiliation:
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Department of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts 02111, USA. carol.kumamoto@tufts.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Biofilms / growth & development* Candida albicans / genetics, growth & development*, pathogenicity* Candidiasis / microbiology, pathology Fungal Proteins / genetics, metabolism Gene Expression Regulation, Fungal* Humans Hyphae / growth & development* Infant Infant, Newborn Rabbits Rats Surface Properties |
| Grant Support | |
ID/Acronym/Agency:
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AI38591/AI/NIAID NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Fungal Proteins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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