Document Detail


Alternative Candida albicans lifestyles: growth on surfaces.
MedLine Citation:
PMID:  16153165     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Candida albicans, an opportunistic fungal pathogen, causes a wide variety of human diseases such as oral thrush and disseminated candidiasis. Many aspects of C. albicans physiology have been studied during liquid growth, but in its natural environment, the gastrointestinal tract of a mammalian host, the organism associates with surfaces. Growth on a surface triggers several behaviors, such as biofilm formation, invasion, and thigmotropism, that are important for infection. Recent discoveries have identified factors that regulate these behaviors and revealed the importance of these behaviors for pathogenesis.
Authors:
Carol A Kumamoto; Marcelo D Vinces
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Review    
Journal Detail:
Title:  Annual review of microbiology     Volume:  59     ISSN:  0066-4227     ISO Abbreviation:  Annu. Rev. Microbiol.     Publication Date:  2005  
Date Detail:
Created Date:  2005-09-12     Completed Date:  2006-01-06     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0372370     Medline TA:  Annu Rev Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  113-33     Citation Subset:  IM    
Affiliation:
Department of Molecular Biology and Microbiology, Tufts University, Boston, Massachusetts 02111, USA. carol.kumamoto@tufts.edu
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Biofilms / growth & development*
Candida albicans / genetics,  growth & development*,  pathogenicity*
Candidiasis / microbiology,  pathology
Fungal Proteins / genetics,  metabolism
Gene Expression Regulation, Fungal*
Humans
Hyphae / growth & development*
Infant
Infant, Newborn
Rabbits
Rats
Surface Properties
Grant Support
ID/Acronym/Agency:
AI38591/AI/NIAID NIH HHS
Chemical
Reg. No./Substance:
0/Fungal Proteins

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