| Alternate strategies for improving iron nutrition: lessons from recent research. | |
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MedLine Citation:
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PMID: 11509109 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Strategies such as dietary diversification and food fortification have yielded significant results in controlling iron deficiency anaemia in developed countries. Reducing the prevalence of iron deficiency anaemia in developing countries is still a matter of importance. The major factors responsible for iron deficiency anaemia in the vulnerable segments of developing countries are reduced intake and poor bioavailability of dietary iron. Dietary diversification and food-based approaches pose considerable challenges before they can be implemented on a wide scale. Anaemia control programmes based on the administration of prophylactic doses of iron and folic acid tablets have been widely implemented. As the programmes were not effective in countries such as India, the dosage of iron was increased. The role of excess iron in causing intestinal oxidative stress has drawn attention to other approaches of iron supplementation. Prophylactic administration of iron along with antioxidants like vitamins E and C or foods rich in these vitamins is one such strategy. To reduce the intestinal oxidative stress, intermittent supplementation of iron is being considered. The potential benefits and shortcomings of these approaches are reviewed. |
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Authors:
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K Madhavan Nair |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The British journal of nutrition Volume: 85 Suppl 2 ISSN: 0007-1145 ISO Abbreviation: Br. J. Nutr. Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-08-17 Completed Date: 2001-08-30 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372547 Medline TA: Br J Nutr Country: England |
Other Details:
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Languages: eng Pagination: S187-91 Citation Subset: IM |
Affiliation:
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Department of Biophysics, National Institute of Nutrition, Indian Council of Medical Research, Jamai Osmania P.O., Hyderabad - 500007, India. nairthayil@rediff.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Anemia, Iron-Deficiency
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drug therapy,
prevention & control Antioxidants / administration & dosage Ascorbic Acid / administration & dosage Developing Countries* Dietary Supplements* Food, Fortified Health Policy* Humans India Intestinal Absorption Intestinal Mucosa / metabolism Iron / metabolism* Micronutrients* Oxidative Stress Sodium Chloride |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Micronutrients; 50-81-7/Ascorbic Acid; 7439-89-6/Iron; 7647-14-5/Sodium Chloride |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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