| Altering end-to-side anastomosis junction hemodynamics: the effects of flow-splitting. | |
| | |
MedLine Citation:
|
PMID: 16337824 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The long-term patency rate of peripheral artery bypass grafts remains low. Several theories exist which attempt to explain the disease forming mechanisms at the disease prone distal junction of the bypass graft. Common to these theories is that abnormal hemodynamics and wall mechanics contribute to the development of disease at the junction. This study describes a means by which the hemodynamics in the end-to-side anastomosis can be altered by inserting a flow-split into the junction, the function of which is to divert the flow away from the artery bed and toward the sidewalls. Velocity vectors through the junction are significantly altered, and artery centreline WSS magnitudes decrease by up to 36% during the deceleration phase of the flow pulse. Corresponding wall shear stress gradients are found to decrease by 49%. However, locations along the artery sidewall have been identified with increased WSS. It is possible to significantly alter junction hemodynamics using a flow-splitter. |
| | |
Authors:
|
T O'Brien; M Walsh; T McGloughlin |
Related Documents
:
|
18199564 - Changes in cerebrospinal fluid and blood lactate concentrations after stent-graft impla... 8270074 - The uptake of platelets, fibrinogen and leucocytes in eptfe vascular grafts in relation... 2753114 - Allografts of cns tissue possess a blood-brain barrier. i. grafts of medial preoptic ar... 309974 - Selective arterialization of the coronary venous system. encouraging long-term flow eva... 9804534 - Stable blood lubricated hydrodynamic journal bearing with magnetic loading. 9174114 - The regulation of cd11b integrin levels on human blood leukocytes and leukotriene b4-st... |
Publication Detail:
|
Type: Journal Article Date: 2005-12-07 |
Journal Detail:
|
Title: Medical engineering & physics Volume: 28 ISSN: 1350-4533 ISO Abbreviation: Med Eng Phys Publication Date: 2006 Sep |
Date Detail:
|
Created Date: 2006-06-12 Completed Date: 2006-10-17 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9422753 Medline TA: Med Eng Phys Country: England |
Other Details:
|
Languages: eng Pagination: 727-33 Citation Subset: IM |
Affiliation:
|
Centre for Applied Biomedical Engineering Research, Materials and Surface Science Institute, Department of Mechanical Engineering, University of Limerick, Limerick, Ireland. thomas.obrien@ul.ie |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Anastomosis, Surgical
/
adverse effects,
methods* Biomedical Engineering Femoral Artery / physiopathology*, surgery* Hemodynamics Humans Models, Cardiovascular Regional Blood Flow |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Real-time RT-PCR quantitative assays and postmortem degradation profiles of erythropoietin, vascular...
Next Document: Questions regarding environmental mercury release, special education rates, and autism disorder: an ...