| Altered temporal peripapillary retinal flow in patients with disc hemorrhages. | |
| | |
MedLine Citation:
|
PMID: 20635187 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: To investigate whether any peripapillary retinal blood flow changes are related to disc hemorrhage (DH). METHODS: The study included 21 eyes of 21 patients, of which 14 eyes had glaucoma. All eyes were examined at the time of detection of DH and again 6 months later. Blood flow in the peripapillary retina was measured by scanning laser Doppler flowmetry (Heidelberg Retina Flowmeter), with four adjacent images focused on the peripapillary nerve fiber layer obtained. Retinal perfusion was calculated in arbitrary units by automatic full-field perfusion image analysis. The mean of all four rectangles representing the whole temporal peripapillary retina plus the rectangle representing the area of DH served for analysis. RESULTS: The mean of measurements in all four areas revealed a statistically significant increase in mean flow (MF), systolic flow (SF), and diastolic flow (DF), and a decrease in pulsation index (PI). The rectangle representing the area of DH showed a significant increase in MF, but the SF increase was of borderline significance. Changes in DF and PI did not reach statistical significance. CONCLUSIONS: Results indicate reduced flow at the time of DH and increased flow after resorption. |
| | |
Authors:
|
Leena Kurvinen; Mika Harju; Jukka Saari; Eija Vesti |
Related Documents
:
|
11316707 - Factors affecting pulsatile ocular blood flow in normal subjects. 453547 - Sem study of the choroid plexus of the lateral ventricle in the cat. 8287997 - The effect of acetazolamide on the retinal circulation. 10896337 - Mechanisms of fluid accumulation in retinal edema. 18789987 - Pharmacokinetics of proline-rich tripeptides in the pig. 22019727 - Integrated strategies for allogeneic blood saving in major elective surgery. |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-16 |
Journal Detail:
|
Title: Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie Volume: 248 ISSN: 1435-702X ISO Abbreviation: Graefes Arch. Clin. Exp. Ophthalmol. Publication Date: 2010 Dec |
Date Detail:
|
Created Date: 2010-11-05 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8205248 Medline TA: Graefes Arch Clin Exp Ophthalmol Country: Germany |
Other Details:
|
Languages: eng Pagination: 1771-5 Citation Subset: IM |
Affiliation:
|
Helsinki University Eye Hospital, PO Box 220, 00029, Helsinki, Finland. leena.kurvinen@fimnet.fi |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Blood Flow Velocity Female Glaucoma / physiopathology* Humans Intraocular Pressure Laser-Doppler Flowmetry Male Middle Aged Nerve Fibers / pathology Optic Disk / blood supply* Optic Nerve Diseases / physiopathology* Regional Blood Flow / physiology Retinal Ganglion Cells / pathology Retinal Hemorrhage / physiopathology* Retinal Vessels / physiology* Tonometry, Ocular |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The status of olfactory function and the striatal dopaminergic system in drug-induced parkinsonism.
Next Document: Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previo...