Document Detail

Altered early left ventricular diastolic cardiac function in the premature infant.
MedLine Citation:
PMID:  3591697     Owner:  NLM     Status:  MEDLINE    
Developmental changes in diastolic ventricular function were assessed in 31 premature infants and in 10 normal-term infants. They were studied during the first 72 hours of life using instantaneous rates of change of left ventricular (LV) cavity dimension, derived from M-mode echocardiography. Maximal velocity of lengthening of the LV cavity was significantly lower in premature infants (38 +/- 7 mm/s) than in term infants (88 +/- 15 mm/s). This variable increased with increasing maturity over the 4 gestational age groups evaluated (r = 0.87). This index normalized for instantaneous LV dimension was lower in the most immature infants (4.5 +/- 1 s-1) than in term infants (6.8 +/- 2 s-1). Eight of the premature infants were studied serially at 1, 3 and 7 days of age. Maximal velocity of lengthening divided by stroke dimension improved from 12.9 +/- 2 s-1 at 1 day of age to 16.5 +/- 3 s-1 at 7 days. These results suggest depressed early diastolic function in premature infants.
R S Appleton; T P Graham; R B Cotton; G A Moreau; R J Boucek
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The American journal of cardiology     Volume:  59     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  1987 Jun 
Date Detail:
Created Date:  1987-07-21     Completed Date:  1987-07-21     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1391-4     Citation Subset:  AIM; IM    
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MeSH Terms
Gestational Age
Heart / physiology*,  physiopathology
Heart Ventricles
Infant, Newborn
Infant, Premature*
Respiratory Distress Syndrome, Newborn / physiopathology
Time Factors

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