Document Detail


Altered coriolis stress susceptibility in essential hypertension.
MedLine Citation:
PMID:  1930846     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Patients with hypertension frequently have vague complaints of dizziness and many other symptoms experienced by healthy individuals with motion sickness. We examined vestibular function in patients with essential hypertension, and we determined whether patients with essential hypertension are more prone to motion sickness using Coriolis stress testing. Vestibular function and Coriolis stress susceptibility were measured in 12 normotensive (NT) and seven asymptomatic patients with mild essential hypertension (HT). The Coriolis stress susceptibility index (CSSI) was calculated from the number of head movements in the four cardinal directions an individual could complete while being rotated in a computerized chair at increasing velocity before they developed motion sickness. The patients with hypertension had normal vestibular function and normal vestibuloocular responses as measured by standard techniques. Subjects with hypertension had significantly decreased Coriolis stress susceptibility scores compared to normotensive subjects (NT, 29.70 +/- 4.8; v HT, 5.48 +/- 2.0, P less than .001) and significantly decreased suppression of postrotatory nystagmus (NT, 44.5% +/- 3.8; v HT, 19.1% +/- 6.9, P less than .05). Medical treatment of hypertension did not result in an increased tolerance to provocative stimuli for motion sickness. It is suggested from our data that an increased susceptibility to motion sickness and abnormal vestibular responses to normal motion may account for many of the vague symptoms of "dizziness" reported by a large number of hypertensive patients.
Authors:
W Lockette; N Shepard; A Lyos; T Boismier; A Mers
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  American journal of hypertension     Volume:  4     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  1991 Aug 
Date Detail:
Created Date:  1991-11-26     Completed Date:  1991-11-26     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  645-50     Citation Subset:  IM; S    
Affiliation:
Department of Medicine, Wayne State University Medical School, Detroit, MI 48201.
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MeSH Terms
Descriptor/Qualifier:
Adult
Coriolis Force*
Disease Susceptibility / pathology
Female
Humans
Hypertension / pathology,  physiopathology*
Male
Middle Aged
Motion Sickness / physiopathology*
Vestibule, Labyrinth / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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