Document Detail

Alterations of myocardial ultrasonic tissue characterization by coronary angioplasty in patients with chronic stable coronary artery disease.
MedLine Citation:
PMID:  11597359     Owner:  NLM     Status:  MEDLINE    
We conducted a study to delineate the alterations in the cyclic changes of myocardial ultrasonic integrated backscatter (IBS) in patients receiving angioplasty for chronic coronary artery disease. Ultrasonic tissue characterization (UTC) and dobutamine stress echocardiography were performed in 43 patients before and 24 h after angioplasty, as well as before the follow-up angiography 3 months later. For segments being normokinetic with ischemic burden, the blunted amplitude and increased nadir deviation of IBS cyclic modulation recovered soon after angioplasty. For dyssynergic segments with contractile reserve, the angioplasty rebuilt the amplitude before the wall motion recovered, but corrected the nadir deviation tardily. In both circumstances, the coronary restenosis abolished the initial restoration. Those nonviable segments persistently revealed large deviations and small weighted amplitudes irrelevant to coronary lesions. The progress of myocardial ischemia, the development of wall motion dyssynergy and, then, the loss of viability, show different patterns of alterations in UTC after alleviating coronary obstructions.
L C Lin; H L Kao; C C Wu; Y L Ho; Y T Lee
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in medicine & biology     Volume:  27     ISSN:  0301-5629     ISO Abbreviation:  Ultrasound Med Biol     Publication Date:  2001 Sep 
Date Detail:
Created Date:  2001-10-12     Completed Date:  2001-12-07     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0410553     Medline TA:  Ultrasound Med Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  1191-8     Citation Subset:  IM    
Department of Internal Medicine, Cardiology Section, National Taiwan University Hospital, No. 7, Chung-Shan S. Road, Taipei, Taiwan.
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MeSH Terms
Chronic Disease
Coronary Angiography
Coronary Artery Disease / physiopathology,  surgery*,  ultrasonography*
Coronary Restenosis / physiopathology,  ultrasonography
Cross-Sectional Studies
Echocardiography, Stress
Middle Aged
Myocardial Contraction / physiology*
Myocardial Ischemia / physiopathology,  ultrasonography

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