Document Detail


Alterations of membrane glycoproteins in malignant cells.
MedLine Citation:
PMID:  223919     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Comparisons have been made of the carbohydrates bound to membrane proteins of control and malignant cells in culture. It has been found that most individual glycoproteins of control and malignant cells differ in their carbohydrate components. Differences between control and malignant cells have been foundin the glycoproteins of the various membrane systems (surface, nucleus, mitochondria, endoplasmic reticulum). It is suggested that the extensive changes in bound carbohydrates of the malignant cell permit the cell to live and divide but isolate the cell functionally. The extensive structural changes may also be responsible for the cascading of involvement of various processes within the malignant cell.
Authors:
L Warren; C A Buck; G P Tuszynski
Related Documents :
6601359 - Non-hodgkin's lymphoma in northwestern kyushu island of japan. clinicopathological stud...
3675799 - Relation of quantitative features of visually normal intermediate cells in cervical int...
22373659 - Differential expression of pai-rbp1, c1orf142, and cotl1 in non-small cell lung cancer ...
16540649 - Lysophosphatidic acid is constitutively produced by human peritoneal mesothelial cells ...
1701599 - Goblet-like cells in atrophic vaginal smears and their histologic correlation. possible...
11072949 - Detection of rare malignant cells and their apoptotic fragments in cerebrospinal fluid.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Developments in biological standardization     Volume:  42     ISSN:  0301-5149     ISO Abbreviation:  Dev. Biol. Stand.     Publication Date:  1979  
Date Detail:
Created Date:  1979-10-26     Completed Date:  1979-10-26     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0427140     Medline TA:  Dev Biol Stand     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  177-82     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Avian Sarcoma Viruses
Carbohydrates / analysis
Cell Line
Cell Transformation, Neoplastic
Cell Transformation, Viral
Cricetinae
Glycopeptides / analysis
Glycoproteins / analysis*
Kidney
Membrane Proteins / analysis*
Neoplasm Proteins / analysis*
Chemical
Reg. No./Substance:
0/Carbohydrates; 0/Glycopeptides; 0/Glycoproteins; 0/Membrane Proteins; 0/Neoplasm Proteins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Multiplication of normal and virus-infected diploid cells cultivated on microcarriers.
Next Document:  A human neoplastic hematopoietic cell line producing a fibroblast type of interferon.