Document Detail


Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR.
MedLine Citation:
PMID:  23083999     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We evaluated the presence of HtrA1 in maternal plasma of normal pregnancies and of pregnancies complicated by preeclampsia (PE) without and with Intrauterine Growth Restriction (IUGR). We demonstrate that HtrA1 maternal plasma levels show significant different concentrations in first, second and third trimester of gestation and that HtrA1 concentration increases in maternal plasma of gestations complicated by PE with IUGR compared with control maternal plasma matched for gestational age. Based on these data high maternal plasma levels of HtrA1 could be considered as a possible marker of an occurring IUGR in preeclamptic women.
Authors:
D Marzioni; T Lorenzi; E Altobelli; S R Giannubilo; F Paolinelli; C Tersigni; C Crescimanno; V Monsurrò; A L Tranquilli; N Di Simone; M Castellucci
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-17
Journal Detail:
Title:  Placenta     Volume:  -     ISSN:  1532-3102     ISO Abbreviation:  Placenta     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8006349     Medline TA:  Placenta     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ltd. All rights reserved.
Affiliation:
Department of Experimental and Clinical Medicine, Università Politecnica delle Marche, via Tronto, 10/a, I-60020 Ancona, Italy. Electronic address: d.marzioni@univpm.it.
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