Document Detail

Alterations of leptin and ghrelin serum concentrations in renal disease: simple epiphenomena?
MedLine Citation:
PMID:  15809831     Owner:  NLM     Status:  MEDLINE    
The hypothesis that alterations of serum concentrations of the anorexigenic adipose tissue-derived hormone leptin or the orexigenic peptide ghrelin might help to regain appetite and fight malnutrition in patients with chronic renal failure cannot be confirmed at present. For the future, however, strategies interfering with signal transduction of these peptides in the hypothalamus might be more promising and should be investigated and further developed.
Jörg Dötsch; Kai Nüsken; Michael Schroth; Wolfgang Rascher; Udo Meissner
Publication Detail:
Type:  Editorial; Review     Date:  2005-04-05
Journal Detail:
Title:  Pediatric nephrology (Berlin, Germany)     Volume:  20     ISSN:  0931-041X     ISO Abbreviation:  Pediatr. Nephrol.     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-12     Completed Date:  2005-09-15     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8708728     Medline TA:  Pediatr Nephrol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  701-6     Citation Subset:  IM    
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MeSH Terms
Disease Progression
Kidney Diseases / blood*,  physiopathology
Kidney Failure, Chronic / blood,  physiopathology
Leptin / blood*
Osmolar Concentration
Peptide Hormones / blood*
Uremia / blood,  physiopathology
Reg. No./Substance:
0/Ghrelin; 0/Leptin; 0/Peptide Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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