Document Detail


Alterations induced by a single defibrillating shock applied through a chronically implanted catheter electrode.
MedLine Citation:
PMID:  6854186     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In ten beagles ranging in weight from 7.4 to 13.0 kg, a defibrillating shock of 10 A (three dogs), 20 A (four dogs), or 30 A (three dogs) intensity was applied through a chronically implanted right ventricular catheter electrode. Ten-lead ECG, right ventricular electrogram, and right ventricular impedance were recorded prior to, immediately following, and 48 hours post-shock. A single shock of 10 A, 20 A, and 30 A intensity succeeded in defibrillating nine of ten dogs. One dog required two 20 A shocks to defibrillate. No shock was fatal. Post-shock arrhythmias increased in duration and severity as the shock strength increased. ECG vector analysis suggested damage to the right ventricle in eight of ten dogs. The impedance signal amplitude increased directly after the shock, but dropped below control level by 200 seconds post-shock and remained below control by 48 hours post-shock. Pale areas of shock-induced myocardial necrosis were concentrated in the right ventricular walls adjacent to the distal electrode. The mean weight of necrotic myocardium was 0.043 + 0.006 grams at 10 A, 1.203 + 0.268 grams at 20 A, and 1.397 + 1.218 grams at 30 A (mean + sd). Defibrillation was effective after long-term implantation. The alterations sustained from defibrillation were minimized by using a low intensity shock.
Authors:
M A Barker-Voelz; J F Van Vleet; W A Tacker; J D Bourland; L A Geddes; M P Schollmeyer
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of electrocardiology     Volume:  16     ISSN:  0022-0736     ISO Abbreviation:  J Electrocardiol     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0153605     Medline TA:  J Electrocardiol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  167-79     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Dogs
Electric Countershock / instrumentation*
Electrocardiography*
Electrodes, Implanted
Heart Ventricles / pathology,  physiopathology
Myocardium / pathology
Necrosis
Ventricular Fibrillation / pathology,  physiopathology,  therapy*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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