| Alterations in sodium metabolism as an etiological model for hypertension. | |
MedLine Citation:
|
PMID: 8527348 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
An adequate matching for race, sex, stage of the menstrual cycle, family history of hypertension, and the amount of sodium and other electrolytes in the diet should be a prerequisite for valid conclusions when interpreting the erythrocyte concentration and fluxes of sodium in essential hypertensive patients in comparison with normal subjects. Alterations in intracellular sodium concentration and transmembrane sodium transport systems as causes of essential hypertension are postulated. This review article describes how this abnormal sodium and calcium metabolism translates into increased systemic vascular resistance through altered vasoactive responses and/or vasculature structural changes. |
Authors:
|
P Lijnen |
Related Documents
:
|
10638388 - Influence of food intake on electrocardiograms of healthy male volunteers. 3384468 - Renal nerves and the development of dahl salt-sensitive hypertension. 8229908 - The effects of sodium loading on blood pressure and pain responses to the cold pressor ... 7140008 - The effect of sodium intake on blood pressure related to the age of the patients. 9137228 - Relation of hemodynamic volume load to arterial and cardiac size. 9194518 - No effect of genetic variation at the angiotensinogen locus on ambulatory blood pressur... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
|
Title: Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy Volume: 9 ISSN: 0920-3206 ISO Abbreviation: Cardiovasc Drugs Ther Publication Date: 1995 Jun |
Date Detail:
|
Created Date: 1996-02-01 Completed Date: 1996-02-01 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 8712220 Medline TA: Cardiovasc Drugs Ther Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 377-99 Citation Subset: IM |
Affiliation:
|
Department of Molecular and Cardiovascular Research, University of Leuven, Belgium. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Antiporters
/
metabolism*,
physiology Bicarbonates / metabolism Blood Pressure / physiology Calcium / metabolism Chlorides / metabolism Erythrocytes / cytology, metabolism Humans Hypertension / etiology*, metabolism Ion Transport Lithium / metabolism* Sodium / metabolism* Sodium-Hydrogen Antiporter / metabolism*, physiology Sodium-Potassium-Exchanging ATPase / metabolism Vascular Resistance / physiology |
| Chemical | |
Reg. No./Substance:
|
0/Antiporters; 0/Bicarbonates; 0/Chlorides; 0/Sodium-Hydrogen Antiporter; 0/sodium-lithium countertransporter; 7439-93-2/Lithium; 7440-23-5/Sodium; 7440-70-2/Calcium; EC 3.6.3.9/Sodium-Potassium-Exchanging ATPase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: A two-stage estimation of structural equation models with continuous and polytomous variables.
Next Document: A double-blind comparison of once-daily metoprolol controlled-release and atenolol in the treatment ...