Document Detail


Alterations in lipidic metabolism in hemodialysis patients.
MedLine Citation:
PMID:  22811228     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Background: Chronic kidney failure is associated with dyslipidemia and accelerated atherosclerosis. Aim: To study lipidic metabolism alterations in patients with chronic kidney failure on hemodialysis. Methods: The study interested 45 hemodialysis patients with a mean age of 49.04 ±15.92 years old and 45 healthy controls. A blood sample was collected from each patient and control to measure total cholesterol, triglycerides, HDL- cholesterol, LDL-cholesterol, apolipoproteins AI and B100, lipoprotein (a) and C Reactive Protein. Results: A significant increase of serum triglycerides (p= 0.002), lipoprotein (a) (p = 0.001) and C Reactive Protein (p = 0.008) was observed in patients when compared with healthy controls. A significant decrease of serum total cholesterol (p=0.01), HDLcholesterol (p<0.001), LDL-cholesterol (p=0.005) and apolipoprotein AI (p<0.001) was also observed in patients. Conclusion: Disorders of lipidic metabolism are frequent in hemodialysis patients. These alterations can lead to cardiovascular disease in uremic patients.
Authors:
Ines Kharrat; Aouatef Jmal; Lobna Jmal; Zeineb Amira; Walid Ben Cheikh; Ferid Ben Bourouba; Lotfi Sahnoun; Monia Abdennebi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  La Tunisie médicale     Volume:  90     ISSN:  0041-4131     ISO Abbreviation:  Tunis Med     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-07-19     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413766     Medline TA:  Tunis Med     Country:  Tunisia    
Other Details:
Languages:  eng     Pagination:  537-41     Citation Subset:  IM    
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