| Alterations in lipidic metabolism in hemodialysis patients. | |
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MedLine Citation:
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PMID: 22811228 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Chronic kidney failure is associated with dyslipidemia and accelerated atherosclerosis. Aim: To study lipidic metabolism alterations in patients with chronic kidney failure on hemodialysis. Methods: The study interested 45 hemodialysis patients with a mean age of 49.04 ±15.92 years old and 45 healthy controls. A blood sample was collected from each patient and control to measure total cholesterol, triglycerides, HDL- cholesterol, LDL-cholesterol, apolipoproteins AI and B100, lipoprotein (a) and C Reactive Protein. Results: A significant increase of serum triglycerides (p= 0.002), lipoprotein (a) (p = 0.001) and C Reactive Protein (p = 0.008) was observed in patients when compared with healthy controls. A significant decrease of serum total cholesterol (p=0.01), HDLcholesterol (p<0.001), LDL-cholesterol (p=0.005) and apolipoprotein AI (p<0.001) was also observed in patients. Conclusion: Disorders of lipidic metabolism are frequent in hemodialysis patients. These alterations can lead to cardiovascular disease in uremic patients. |
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Authors:
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Ines Kharrat; Aouatef Jmal; Lobna Jmal; Zeineb Amira; Walid Ben Cheikh; Ferid Ben Bourouba; Lotfi Sahnoun; Monia Abdennebi |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: La Tunisie médicale Volume: 90 ISSN: 0041-4131 ISO Abbreviation: Tunis Med Publication Date: 2012 Jul |
Date Detail:
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Created Date: 2012-07-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0413766 Medline TA: Tunis Med Country: Tunisia |
Other Details:
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Languages: eng Pagination: 537-41 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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