| Alterations in lipid metabolism of developing muscle cells in culture. | |
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MedLine Citation:
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PMID: 760796 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Embryonic chick muscle cells in the infused (myoblast) and fused (myotube) states differentially incorporate [3H]palmitic acid into their cellular lipids. Myoblasts incorporated [3H]palmitic acid 6--7-fold greater than myotubes in the triglyceride fraction. The endogenous triglyceride levels, however, were similar for the two developmental stages indicating increased triglyceride turnover in the myoblast compared to that of the myotube. Myotubes showed an increased incorporation of [3H]palmitic acid into sphingomyelin compared to myoblasts. Myoblasts and myotubes had a similar phospholipid composition. The data indicate that fusion is characterized by a decrease in triglyceride turnover possibly reflecting a shift from oxidative to glycolytic metabolism to coincide with the fusion process. |
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Authors:
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P B Smith; R A Finch |
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Publication Detail:
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Type: Comparative Study; Journal Article |
Journal Detail:
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Title: Biochimica et biophysica acta Volume: 572 ISSN: 0006-3002 ISO Abbreviation: Biochim. Biophys. Acta Publication Date: 1979 Jan |
Date Detail:
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Created Date: 1979-04-25 Completed Date: 1979-04-25 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0217513 Medline TA: Biochim Biophys Acta Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 139-45 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cells, Cultured Chick Embryo Fatty Acids / analysis Lipid Metabolism* Muscles / cytology, embryology, metabolism* Palmitic Acids / metabolism Phospholipids / metabolism Triglycerides / metabolism |
| Chemical | |
Reg. No./Substance:
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0/Fatty Acids; 0/Palmitic Acids; 0/Phospholipids; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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