Document Detail

Alterations in the dimensions of aortopulmonary septum in hypertensive subjects.
MedLine Citation:
PMID:  14621180     Owner:  NLM     Status:  MEDLINE    
The neural crest origin of the aortopulmonary septum has led us to investigate the septum for a special function, and we designed the present study to assess the alteration, if any, in the dimensions of the aortopulmonary septum in hypertension. The dimensions of the aortopulmonary septum were measured by echocardiography in 36 hypertensive and 36 age- and sex-matched normotensive subjects. Echocardiographic examination included measurement of the cross-sectional area of the aortopulmonary septum with standard two-dimensional views from the parasternal windows. Standardization of this dimension with appropriate cardiac measurements such as aortic and internal left ventricular diameters was also performed to provide growth-independent estimates of septal size. The average area of the septum in the hypertensive group was 2.183 +/- 0.391 cm2, significantly lower than that in the normotensive group (2.370 +/- 0.415 cm2). There were also significant differences in the area of the aortopulmonary septum between the groups when the values were standardized with internal left ventricular diameters. In conclusion, these data confirm that the aortopulmonary septum is smaller in hypertensive than in normotensive humans. This difference might be the result of a possible function of the aortopulmonary septum in blood pressure regulation.
M Kemal Irmak; Kursat Erinc; Fatih Yazar; Mehmet Uzun; Ersin Fadillioglu; Mustafa Ozer
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Hypertension research : official journal of the Japanese Society of Hypertension     Volume:  26     ISSN:  0916-9636     ISO Abbreviation:  Hypertens. Res.     Publication Date:  2003 Oct 
Date Detail:
Created Date:  2003-11-17     Completed Date:  2004-06-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9307690     Medline TA:  Hypertens Res     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  783-7     Citation Subset:  IM    
Department of Histology and Embryology, Gulhane Military Medical Academy, Ankara, Turkey.
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MeSH Terms
Aorta / pathology*,  ultrasonography
Hypertension / pathology*,  ultrasonography
Middle Aged
Pulmonary Artery / pathology*,  ultrasonography

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