Document Detail


Alterations in cardiac rate and rhythm in miniature swine during simulated aerial combat maneuver +Gz stress.
MedLine Citation:
PMID:  6162448     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Electrocardiograms (McFee-axial reference system) were recorded from 18 chronically instrumented, conscious, female miniature swine before, during, and after exposures to +Gz stress. The animals were exposed to five simulated aerial combat maneuver (SACM) type acceleration profiles which spanned approximately 106 s and included two 5-s +9Gz peaks. A 5-min rest period separated each SACM exposure. Maximum heart rates during +Gz decreased over the course of the 5 SACM's-241 +/- 4 b/m and 224 +/- 5 b/m for the first and last exposures, respectively. Resting heart rates obtained 5 min after each SACM exposure were steadily increased from a control of 86 +/- 5 b/m to a final of 129 +/- 8b/m. Of the 18 animals studied, 10 developed arrhythmias during +Gz, or within the first minute after +Gz exposure. Arrhythmias exhibited included premature atrial and ventricular contractions, intraventricular conduction defects, sinus arrhythmias, premature junctional contractions, atrial bigeminy, ectopic atrial and ventricular rhythms, complete A-V dissociation, left anterior arborization-block, and junctional rhythms with aberrant conduction. While arrhythmias were not uncommonly observed during +Gz, most occurred at the end of the SACM profile or immediately following the SACM.
Authors:
W M Witt; M H Laughlin; J W Burns
Related Documents :
6685488 - Effects of diltiazem on vulnerability to atrial and ventricular reentrant arrhythmias i...
1708198 - Antiarrhythmic actions of tocainide in canine models of previous myocardial infarction.
12653188 - Modulatory influences of ventilatory disorders on electrical stability of the rat heart.
54578 - Oral disopyramide in prophylaxis of arrhythmias following myocardial infarction.
356578 - Efficacy of lidocaine in preventing primary ventricular fibrillation within 1 hour afte...
12411458 - Kallikrein gene delivery improves cardiac reserve and attenuates remodeling after myoca...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Aviation, space, and environmental medicine     Volume:  51     ISSN:  0095-6562     ISO Abbreviation:  Aviat Space Environ Med     Publication Date:  1980 Oct 
Date Detail:
Created Date:  1981-04-13     Completed Date:  1981-04-13     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7501714     Medline TA:  Aviat Space Environ Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1114-8     Citation Subset:  IM; S    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Arrhythmias, Cardiac*
Cardiac Complexes, Premature / physiopathology
Electrocardiography
Female
Gravitation*
Gravity Suits / standards
Heart Conduction System / physiopathology
Heart Rate*
Stress, Physiological
Swine / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Animal experiments for intratumoral chemotherapy with bleomycin (author's transl)
Next Document:  In vitro translation of maize ADH: evidence for the anaerobic induction of mRNA.