| Alterations in amino acid concentrations in the plasma and muscle in human subjects during 24 h of simulated adventure racing. | |
| | |
MedLine Citation:
|
PMID: 22350359 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
This investigation was designed to evaluate changes in plasma and muscle levels of free amino acids during an ultra-endurance exercise and following recovery. Nine male ultra-endurance trained athletes participated in a 24-h standardized endurance trial with controlled energy intake. The participants performed 12 sessions of running, kayaking and cycling (4 × each discipline). Blood samples were collected before, during and after exercise, as well as after 28 h of recovery. Muscle biopsies were taken before the test and after exercise, as well as after 28 h of recovery. During the 24-h exercise, plasma levels of branched-chain (BCAA), essential amino acids (EAA) and glutamine fell 13, 14 and 19% (P < 0.05), respectively, whereas their concentrations in muscle were unaltered. Simultaneously, tyrosine and phenylalanine levels rose 38 and 50% (P < 0.05) in the plasma and 66 and 46% (P < 0.05) in muscle, respectively. After the 24-h exercise, plasma levels of BCAA were positively correlated with muscle levels of glycogen (r (2) = 0.73, P < 0.05), as was the combined concentrations of muscle tyrosine and phenylalanine with plasma creatine kinase (R (2) = 0.55, P < 0.05). Following 28-h of recovery, plasma and muscle levels of amino acids had either returned to their initial levels or were elevated. In conclusion, ultra-endurance exercise caused significant changes elevations in plasma and muscle levels of tyrosine and phenylalanine, which suggest an increase in net muscle protein breakdown during exercise. There was a reduction in plasma concentrations of EAA and glutamine during exercise, whereas no changes were detected in their muscle concentration after exercise. |
| | |
Authors:
|
Marcus Borgenvik; Marie Nordin; C Mikael Mattsson; Jonas K Enqvist; Eva Blomstrand; Björn Ekblom |
Related Documents
:
|
2553229 - Inclusion body myositis associated with progressive dysphagia: treatment with cricophar... 19041639 - Permeation of several cryoprotectant agents into porcine articular cartilage. 6221879 - Proteoglycan alterations in rabbit knee articular cartilage following physical exercise... 3654339 - Topographical variation of glycosaminoglycan content and cartilage thickness in canine ... 22506219 - Effects of the off-loading brace on the activation of femoral muscles -a preliminary st... 22858629 - Decreased dna fragmentation and apoptotic signaling in soleus muscle of hypertensive ra... 22260889 - Exercise and sedentary habits among adolescents with pcos. 18703769 - The brain injury biomarker vlp-1 is increased in the cerebrospinal fluid of alzheimer d... 15054409 - Effect of prior exercise on lipemia after a meal of moderate fat content. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-2-18 |
Journal Detail:
|
Title: European journal of applied physiology Volume: - ISSN: 1439-6327 ISO Abbreviation: - Publication Date: 2012 Feb |
Date Detail:
|
Created Date: 2012-2-21 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Åstrand Laboratory of Work Physiology, The Swedish School of Sport and Health Sciences, Stockholm, Sweden. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: G tolerance vis-à-vis pressure-distension and pressure-flow relationships of leg arteries.
Next Document: Different modulation pattern of spinal stretch reflex excitability in highly trained endurance runne...