Document Detail

Alterations in QT dispersion in the surface electrocardiogram of female adolescents diagnosed with restricting-type anorexia nervosa.
MedLine Citation:
PMID:  17383499     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: QT dispersion (QTd), defined as the difference between the longest interval and the shortest interval in the 12-lead electrocardiogram (ECG), is a measure of myocardial repolarization inhomogeneity. We assessed QTd in malnourished anorexia nervosa (AN) inpatients and following weight restoration. METHODS: QTd analysis, anthropometric evaluations, and laboratory tests were carried out in 30 malnourished female adolescent AN restricting-type (AN-R) inpatients and following weight restoration. RESULTS: A significant increase was found in weight/height ratio and body mass index from malnourished stage to weight restoration, paralleled by a significant decrease in QTd (70+/-16 vs. 47+/-16 ms; P<.0001). No correlations were found between ECG indices and anthropometric and laboratory measures. CONCLUSION: Elevated QTd in malnourished AN-R inpatients may indicate possible cardiac autonomic imbalance and/or myocardial damage, likely corrected following weight restoration.
Eitan Nahshoni; Abraham Weizman; Amit Yaroslavsky; Anat Toledano; Jacqueline Sulkes; Daniel Stein
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of psychosomatic research     Volume:  62     ISSN:  0022-3999     ISO Abbreviation:  J Psychosom Res     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-03-26     Completed Date:  2007-07-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376333     Medline TA:  J Psychosom Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  469-72     Citation Subset:  IM    
Geha Mental Health Center, Beilinson Campus, Petah Tikva, Israel.
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MeSH Terms
Anorexia Nervosa / diagnosis,  physiopathology*,  psychology,  therapy
Body Mass Index
Follow-Up Studies
Long QT Syndrome / diagnosis,  physiopathology*,  psychology
Patient Admission
Thinness / physiopathology,  psychology,  therapy

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