Document Detail

Alterations of gastrointestinal motility in obesity.
MedLine Citation:
PMID:  15601965     Owner:  NLM     Status:  MEDLINE    
All nutrients are absorbed in the gastrointestinal (GI) system, and GI motility plays a very critical role in the consumption of foods, digestion, and absorption of nutrients. Various segments of the GI tract (esophagus, stomach, and intestines) coordinate in a complex yet precise way to control the process of food consumption, digestion, and absorption of nutrients. GI motility not only regulates the rates at which nutrients are processed and absorbed in the gut but also participates in the control of appetite and satiety. Altered GI motility has been associated with various disease conditions (gastroparesis, etc.) and has been frequently observed in obese patients. The significance of these GI motility alterations in obesity is not fully understood, but they have been considered as potential contributing factors in the development and maintenance of obesity and changed eating behavior. Therapies aimed at regulating GI motility are being actively explored and applied clinically for the management of obese patients. To better understand the pathophysiology of obesity, we systematically reviewed GI motility changes observed in obese conditions. The relationship and pathological significance of these findings, as well as the potential therapies by modification of GI motility, are also discussed.
Jinhong Xing; Jiande D Z Chen
Related Documents :
19533865 - The concentrations of blood sugar and hba1c are significantly higher in g/g homozygotes...
6286395 - Relationship between rate of digestion of foods and post-prandial glycaemia.
11051285 - The glycaemic index of a range of gluten-free foods.
12088525 - Dietary carbohydrate's effects on lipogenesis and the relationship of lipogenesis to bl...
23263225 - Bacterial diversity analysis of zhenjiang yao meat during refrigerated and vacuum-packe...
24894065 - Phthalates and diet: a review of the food monitoring and epidemiology data.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Obesity research     Volume:  12     ISSN:  1071-7323     ISO Abbreviation:  Obes. Res.     Publication Date:  2004 Nov 
Date Detail:
Created Date:  2004-12-16     Completed Date:  2005-03-17     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  9305691     Medline TA:  Obes Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1723-32     Citation Subset:  IM    
Veterans Research Foundation and Transneuronix Inc., Oklahoma City, Oklahoma, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Colon / physiopathology
Gastric Emptying / physiology
Gastroesophageal Reflux / complications,  epidemiology,  physiopathology
Gastrointestinal Motility / physiology*
Intestine, Small / physiopathology
Obesity / complications,  physiopathology*
Stomach / innervation,  physiopathology
Grant Support
1R43-DK063733-01/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Parent-child feeding strategies and their relationships to child eating and weight status.
Next Document:  Polymorphisms in PLIN and hypertension combined with obesity and lipid profiles in Han Chinese.