| Alterations of the cortisol quiescent period after experimental night work with enforced adaptation by bright light and its relation to morningness. | |
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MedLine Citation:
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PMID: 19911191 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A previous study where the delay of the circadian system was induced by bright light that was adjusted to the individual melatonin onset revealed concomitant alterations of the cortisol quiescent period that correlated inversely with morningness. This meta-analysis focuses on the question whether this applies to experimental shift work with fixed light schedules. The analysis bases on data from three laboratory studies where healthy young men [18 evening-, 20 neither-, 11 morning types (MT)] performed three consecutive day shifts and then three consecutive night shifts. Phase assessment procedures were performed after every three shifts to ascertain the diurnal melatonin profile for the quantification of the phase shift and the diurnal cortisol profile for the determination of the cortisol quiescent period. Work was done in 150-200 lx but phase delays were promoted by bright light (1,500-2,000 lx) either by 4-h pulses in the first part of the night or by continuous exposure during the whole night shifts. These different light scenarios caused similar phase delays. Morningness was inversely related to the phase delay and to the alteration of the cortisol quiescent period. The latter became shorter in morning and longer in evening types. Thus, MT are disadvantaged, even if treated with bright light. This suggests that morning-oriented career shift workers might have a higher health risk. These results need to be replicated by directed studies and verified by epidemiological studies. |
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Authors:
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Barbara Griefahn; Sibylle Robens |
Publication Detail:
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Type: Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of applied physiology Volume: 108 ISSN: 1439-6327 ISO Abbreviation: Eur. J. Appl. Physiol. Publication Date: 2010 Mar |
Date Detail:
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Created Date: 2010-02-25 Completed Date: 2010-04-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100954790 Medline TA: Eur J Appl Physiol Country: Germany |
Other Details:
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Languages: eng Pagination: 719-26 Citation Subset: IM |
Affiliation:
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Leibniz Centre for Working Environment and Human Factors, TU Dortmund University, Ardeystr. 67, 44139 Dortmund, Germany. griefahn@ifado.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adaptation, Physiological
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physiology* Adolescent Adult Area Under Curve Arousal / physiology* Circadian Rhythm / physiology* Human Experimentation Humans Hydrocortisone / analysis, metabolism* Light* Male Sleep Disorders, Circadian Rhythm / metabolism, physiopathology Work / physiology* Work Schedule Tolerance / physiology Young Adult |
| Chemical | |
Reg. No./Substance:
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50-23-7/Hydrocortisone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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