Document Detail

Alterations of body temperature, feeding, drinking, and sleep-wake circadian rhythms in Rhesus monkey during a 19 day Spacelab flight simulation.
MedLine Citation:
PMID:  11538507     Owner:  NASA     Status:  MEDLINE    
Previous experiments performed with mammals during spaceflight suggest that microgravity may affect the circadian timekeeping system. However, this system could also be influenced by other factors related to the spaceflight environment, such as the animal compartment. The Rhesus project is a joint program of C.N.E.S. and N.A.S.A in which investigators in various disciplines of physiology will take advantage of flights of the Spacelab to study problems that interest them, using the Rhesus monkey as animal model. The technical characteristics of the Rhesus Research Facility in the Spacelab have been described elsewhere. In order to clarify the influence of the spaceflight environment, other than microgravity itself, on the circadian timekeeping system, we evaluated the characteristics of the circadian rhythms of body temperature, food and water intake, and sleep-wake cycles in Rhesus monkeys during the first 19-day flight simulation of this project.
V H Demaria-Pesce; E Balzamo
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Physiologist     Volume:  36     ISSN:  0031-9376     ISO Abbreviation:  Physiologist     Publication Date:  1993 Feb 
Date Detail:
Created Date:  1996-05-28     Completed Date:  1996-05-28     Revised Date:  2007-08-01    
Medline Journal Info:
Nlm Unique ID:  0401143     Medline TA:  Physiologist     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  S119-20     Citation Subset:  S    
Laboratoire de Neurobiologie des Régulations CNRS URA, Collĕge de France, Paris.
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MeSH Terms
Body Temperature / physiology
Circadian Rhythm / physiology*
Drinking / physiology*
Feeding Behavior / physiology*
Macaca mulatta
Restraint, Physical
Skin Temperature / physiology*
Space Simulation*

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