Document Detail

Alterations of acyl-neuraminic acids on T-lymphocytes in cases of melanoma.
MedLine Citation:
PMID:  3262185     Owner:  NLM     Status:  MEDLINE    
Content and distribution of the different sialic acids on human lymphocytes, isolated from 7-10 ml of fresh human blood, were determined using microanalytical methods, such as HPLC and a colorimetric test. Comparison of the data of patients with melanoma with those of healthy persons shows an evident increase of the sialic acid content combined with a shift of the sialic acid distribution to higher O-acetylated derivatives.
R Holzhauser; H Faillard; W Klose; W Huber; H Stickl; M Landthaler
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Klinische Wochenschrift     Volume:  66     ISSN:  0023-2173     ISO Abbreviation:  Klin. Wochenschr.     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-10-20     Completed Date:  1988-10-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985205R     Medline TA:  Klin Wochenschr     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  540-4     Citation Subset:  IM    
Universität des Saarlandes, Biochemie.
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MeSH Terms
Chromatography, High Pressure Liquid
Melanoma / immunology*
Sialic Acids / metabolism*
Skin Neoplasms / immunology*
T-Lymphocytes / immunology*
Reg. No./Substance:
0/Sialic Acids

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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