Document Detail

Alterations of the Frank orthogonal scalar leads induced by anaphylactic shock in the rabbit.
MedLine Citation:
PMID:  947335     Owner:  NLM     Status:  MEDLINE    
The anaphylactic shock of the rabbit is characterized by an acute right ventricular overload, accompanied by severe alterations of cardiac electrogenesis. During shock, the mean QRS vector, as measured from the algebraic sum of the Q, R, and S deflections on the three leads, shifts to the right, inferiorly and anteriorly. An injury current quickly appears. The TQ vector points away from the right ventricle. A progressive depolarization on the right ventricular wall is displayed by suction electrodes and the suppression of right ventricular hypertension by a cross circulation produces an almost immediate disappearance of the injury current. The geneses of these electrical alterations are briefly discussed. The possibility of an anaphylactic reaction at the level of the coronary arterial wall, previously mentioned in the literature, seems unlikely. The role of the haemodynamic changes and of the increased right ventricular blood pool is thought to be predominant.
J Boland; J Troquet; J P Bleus
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular research     Volume:  10     ISSN:  0008-6363     ISO Abbreviation:  Cardiovasc. Res.     Publication Date:  1976 Jul 
Date Detail:
Created Date:  1976-10-29     Completed Date:  1976-10-29     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0077427     Medline TA:  Cardiovasc Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  474-81     Citation Subset:  IM    
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MeSH Terms
Action Potentials
Anaphylaxis / physiopathology*
Blood Pressure
Cross Circulation
Heart / physiopathology*
Heart Rate
Heart Ventricles / physiopathology
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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