Document Detail

Alprazolam in older depressed inpatients.
MedLine Citation:
PMID:  6133850     Owner:  NLM     Status:  MEDLINE    
Alprazolam, a triazolobenzodiazepine first developed as an anxiolytic, has been shown to be effective in the treatment of depression in several comparison studies with tricyclic antidepressants. This open label study examined the efficacy and safety of alprazolam in patients aged 56-78. Of 18 patients with evaluable data, 12 were responders (improvement greater than or equal to 50% on the Hamilton Depression Rating Scale); 4 patients were partial responders (HAM-D improvement of 25%-49%); and 2 patients were nonresponders. Initial drowsiness was the only side effect observed.
W M Pitts; W E Fann; C Sajadi; S Snyder
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  The Journal of clinical psychiatry     Volume:  44     ISSN:  0160-6689     ISO Abbreviation:  J Clin Psychiatry     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-07-29     Completed Date:  1983-07-29     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7801243     Medline TA:  J Clin Psychiatry     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  213-5     Citation Subset:  IM    
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MeSH Terms
Anti-Anxiety Agents / therapeutic use*
Benzodiazepines / therapeutic use*
Depressive Disorder / drug therapy*,  psychology
Drug Evaluation
Middle Aged
Psychiatric Status Rating Scales
Reg. No./Substance:
0/Anti-Anxiety Agents; 12794-10-4/Benzodiazepines; 28981-97-7/Alprazolam

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