Document Detail


Alpha(2)-blocker helps to avoid systemic to pulmonary shunt in a prostaglandin dependent infant with critical pulmonary valve stenosis.
MedLine Citation:
PMID:  17125639     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 27 days old newborn with critical pulmonary valve stenosis remained prostaglandin (PGE(1)) dependent for 2 weeks after successful balloon valvuloplasty. Only the introduction of Phentolamine in his medication regimen, allowed PGE(1) to be weaned off within days of this therapy. The medication was continued for 4 days and replaced by angiotensin converting enzyme inhibitor (Captopril). Few weeks after the discharge, the patient remained clinically stable with acceptable saturation.
Authors:
Mohammad Omar Galal; Amin Muhammad Arfi; Jameel Al Ata; Arif Hussain; Amjad Kouatli
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of the College of Physicians and Surgeons--Pakistan : JCPSP     Volume:  16     ISSN:  1022-386X     ISO Abbreviation:  J Coll Physicians Surg Pak     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-27     Completed Date:  2007-09-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9606447     Medline TA:  J Coll Physicians Surg Pak     Country:  Pakistan    
Other Details:
Languages:  eng     Pagination:  780-2     Citation Subset:  IM    
Affiliation:
Department of Cardiovascular Diseases, Section of Pediatric Cardiology, King Faisal Specialist Hospital and RC, Jeddah, Saudi Arabia.
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MeSH Terms
Descriptor/Qualifier:
Adrenergic alpha-Antagonists / therapeutic use*
Alprostadil / therapeutic use
Humans
Infant, Newborn
Male
Phentolamine / therapeutic use*
Pulmonary Circulation
Pulmonary Valve Stenosis / congenital*,  drug therapy*,  physiopathology
Vasodilator Agents / therapeutic use
Chemical
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Vasodilator Agents; 50-60-2/Phentolamine; 745-65-3/Alprostadil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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