| Alpha-linolenic acid, long-chain n-3 fatty acids, and neonatal brain development. | |
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MedLine Citation:
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PMID: 1686983 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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There appear to be mechanisms that enable the developing brain to regulate its concentration of 22:6n-3 in response to both dietary deficiencies and excesses. This appears to be true whether the n-3 fatty acids are supplied as 18:3n-3 or the long-chain derivatives, suggesting that the presence of 22:6n-3 during development may be of functional consequence to the operation of the nervous system. Although there is experimental support for specific effects of n-3 fatty acids on retinal function, further studies with better methodological controls are needed before effects on cognitive function in rodents can be considered unequivocal. |
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Authors:
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P E Wainwright |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Nutrition (Burbank, Los Angeles County, Calif.) Volume: 7 ISSN: 0899-9007 ISO Abbreviation: Nutrition Publication Date: 1991 Nov-Dec |
Date Detail:
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Created Date: 1992-04-30 Completed Date: 1992-04-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8802712 Medline TA: Nutrition Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 443-6 Citation Subset: IM |
Affiliation:
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Department of Health Studies, University of Waterloo, Ontario, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Animals, Newborn / growth & development* Brain / growth & development*, metabolism Dietary Fats, Unsaturated / pharmacology Fatty Acids, Unsaturated / physiology*, therapeutic use Humans Linolenic Acids / physiology* alpha-Linolenic Acid |
| Chemical | |
Reg. No./Substance:
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0/Dietary Fats, Unsaturated; 0/Fatty Acids, Unsaturated; 0/Linolenic Acids; 463-40-1/alpha-Linolenic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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