| Alpha interferon treatment in atopic dermatitis. | |
| | |
MedLine Citation:
|
PMID: 8103259 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Eight patients suffering from atopic dermatitis were treated with interferon alpha 2b. They received low or intermediate doses (9-15 x 10(6) U/week) for a short period of time (4-8 weeks), with a moderate improvement of skin lesions in 4 of them and no change or an exacerbation of the disease in the other 4. Among the 4 patients who slightly improved at 4 weeks, 3 did not show any beneficial effect of interferon after 8 weeks. Serum IgE levels, which were increased in all patients before treatment, were not reduced under interferon therapy. This study shows that intermediate doses of interferon alpha 2b are not effective in the short-term treatment of atopic dermatitis. |
| | |
Authors:
|
D Jullien; J F Nicolas; A Frappaz; J Thivolet |
Related Documents
:
|
2576629 - Lack of activity of zidovudine in aids-associated kaposi's sarcoma. 18197359 - Change over time of mortality predictors after haart initiation in a senegalese cohort. 15911439 - Spontaneous recovery of hemoglobin and neutrophil levels in japanese patients on a long... 2792319 - Bone marrow morphology during alpha-interferon treatment in hairy cell leukemia. 11495029 - Changes in histological lesions and serum fibrogenesis markers in chronic hepatitis c p... 9345419 - Long term recombinant interferon alpha treatment in ms with special emphasis to side ef... 17670019 - Triflusal versus oral anticoagulation for primary prevention of thromboembolism after b... 8410449 - Experimental temporomandibular joint disc perforation in the rabbit: a gross morphologi... 16353399 - Development and characterization of an animal model of dental sinusitis. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Acta dermato-venereologica Volume: 73 ISSN: 0001-5555 ISO Abbreviation: Acta Derm. Venereol. Publication Date: 1993 Apr |
Date Detail:
|
Created Date: 1993-09-28 Completed Date: 1993-09-28 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0370310 Medline TA: Acta Derm Venereol Country: SWEDEN |
Other Details:
|
Languages: eng Pagination: 130-2 Citation Subset: IM |
Affiliation:
|
INSERM U.346, Hôpital E. Herriot, Lyon, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Chronic Disease Dermatitis, Atopic / blood, therapy* Female Humans Immunoglobulin E / blood Interferon Alfa-2b / therapeutic use* Male Time Factors Treatment Outcome |
| Chemical | |
Reg. No./Substance:
|
37341-29-0/Immunoglobulin E; 99210-65-8/Interferon Alfa-2b |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dentist's occupational allergic contact dermatitis caused by coconut diethanolamide, N-ethyl-4-tolue...
Next Document: Inflammatory carcinoma masquerading as erythema annulare centrifugum.