Document Detail

Alpha-interferon therapy in a case of probable progressive multifocal leukoencephalopathy.
MedLine Citation:
PMID:  1546522     Owner:  NLM     Status:  MEDLINE    
Probable progressive multifocal leukoencephalopathy (PML) was diagnosed on the basis of clinical picture and magnetic resonance imaging in a 63-year-old man with a complete remission of a non-Hodgkin's lymphoma. After the introduction of intramuscular alpha-interferon therapy, his neurological state and MRI findings showed a clear improvement. Eighteen months after the onset of first symptoms the patient has significantly recovered from both aphasia and motor impairment, and shows only a mild attentional deficit.
C Colosimo; P Lebon; M Martelli; F Tumminelli; F Mandelli
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta neurologica Belgica     Volume:  92     ISSN:  0300-9009     ISO Abbreviation:  Acta Neurol Belg     Publication Date:  1992  
Date Detail:
Created Date:  1992-04-16     Completed Date:  1992-04-16     Revised Date:  2006-04-24    
Medline Journal Info:
Nlm Unique ID:  0247035     Medline TA:  Acta Neurol Belg     Country:  BELGIUM    
Other Details:
Languages:  eng     Pagination:  24-9     Citation Subset:  IM    
International Medical Service, Roma, Italy.
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MeSH Terms
Antineoplastic Combined Chemotherapy Protocols / therapeutic use
Interferon-alpha / therapeutic use*
Leukoencephalopathy, Progressive Multifocal / complications,  diagnosis,  therapy*
Lymphoma, Non-Hodgkin / complications,  drug therapy
Magnetic Resonance Imaging
Middle Aged
Reg. No./Substance:

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