Document Detail


Alpha-hydroxy acids: unapproved uses or indications.
MedLine Citation:
PMID:  15133393     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alpha-hydroxy acids have been used for rejuvenation since ancient times, and now there are several on the market. Depending on the concentration, some have been shown to be effective as peeling agents and for rejuvenation. Glycolic acid and lactic acid are the alpha-hydroxy acids most frequently used in cosmetics, although there are many others used in combination. Some of the most striking advances in dermatology have followed the off-label use of drugs, which is widespread and unavoidable, but a well founded scientific approach to an individual patient's pathology must be emphasized as the number of products, regimens, and adjuncts increases exponentially in the cosmetic field. In this article the authors review some unapproved uses of alpha-hydroxy acids. More published data on the scientific value of these off-label indications that proves whether they are effective or not is needed.
Authors:
Marcia Ramos-e-Silva; Maria Cristina Ribeiro de Castro; Sueli Coelho da Silva Carneiro; W Clark Lambert
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Skinmed     Volume:  3     ISSN:  1540-9740     ISO Abbreviation:  Skinmed     Publication Date:    2004 May-Jun
Date Detail:
Created Date:  2004-05-10     Completed Date:  2004-07-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  101168327     Medline TA:  Skinmed     Country:  United States    
Other Details:
Languages:  eng     Pagination:  141-8     Citation Subset:  IM    
Affiliation:
Sector of Dermatology, HUCFF and School of Medicine, Federal University of Rio de Janeiro, Brazil. ramos.e.silva@dermato.med.br
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MeSH Terms
Descriptor/Qualifier:
Humans
Hydroxy Acids / adverse effects,  pharmacology*
Keratolytic Agents / adverse effects,  pharmacology*
Chemical
Reg. No./Substance:
0/Hydroxy Acids; 0/Keratolytic Agents

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