| Alpha-blockers and urethral pressure in neurological patients. | |
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MedLine Citation:
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PMID: 30197 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 11 patients with upper motor neuron bladder paresis due to spinal trauma, 2 patients with lower motor neuron bladder paresis, and 4 patients with multiple sclerosis, alpha-adrenergic blockade with 10 mg Regitine intravenously decreased the maximum urethral closure pressure to an average of 42%. The decrease was most pronounced in a patient with lower motor neuron bladder paresis and a flaccid pelvic floor. Treatment with phenoxybenzamine was found valuable in patients with multiple sclerosis and poor bladder emptying as well as in patients with lower motor neuron bladder paresis. In patients with detrusorsphincter dyssynergia this treatment was of no value. |
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Authors:
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J Nordling |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Urologia internationalis Volume: 33 ISSN: 0042-1138 ISO Abbreviation: Urol. Int. Publication Date: 1978 |
Date Detail:
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Created Date: 1978-12-29 Completed Date: 1978-12-29 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0417373 Medline TA: Urol Int Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 304-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adrenergic alpha-Antagonists
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pharmacology* Female Humans Male Multiple Sclerosis / physiopathology Paralysis / physiopathology Phenoxybenzamine / pharmacology Phentolamine / pharmacology* Pressure Urethra / drug effects* Urinary Bladder Diseases / physiopathology Urinary Bladder, Neurogenic / physiopathology |
| Chemical | |
Reg. No./Substance:
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0/Adrenergic alpha-Antagonists; 50-60-2/Phentolamine; 59-96-1/Phenoxybenzamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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