| Alpha 1-antitrypsin phenotypes in patients with abdominal aortic aneurysms. | |
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MedLine Citation:
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PMID: 2214739 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The alpha 1-antitrypsin phenotypes were determined in 47 patients with abdominal aortic aneurysms. The MM phenotype was present in 85%, the MS phenotype in 4%, the MZ phenotype in 11%, and the ZZ phenotype not present in any patients. The MZ phenotype occurred significantly more often in patients with aneurysms than would be expected in the general population. The current data would support a genetic mechanism of either autosomal-dominant or multifactorial influences but not an X-linked mechanism for families with a history of abdominal aortic aneurysms. |
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Authors:
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J R Cohen; I Sarfati; L Ratner; D Tilson |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Journal of surgical research Volume: 49 ISSN: 0022-4804 ISO Abbreviation: J. Surg. Res. Publication Date: 1990 Oct |
Date Detail:
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Created Date: 1990-11-16 Completed Date: 1990-11-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0376340 Medline TA: J Surg Res Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 319-21 Citation Subset: IM |
Affiliation:
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Department of Surgery, Long Island Jewish Medical Center, New Hyde Park, New York 11042. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aorta, Abdominal Aortic Aneurysm / genetics* Humans Phenotype* alpha 1-Antitrypsin / genetics* |
| Chemical | |
Reg. No./Substance:
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0/alpha 1-Antitrypsin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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