| Alpha 1-adrenergic stimulation causes Mg2+ release from perfused rat liver. | |
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MedLine Citation:
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PMID: 2540032 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The possibility that Mg2+ mobilization is stimulated in perfused liver by alpha 1-adrenergic agonists was studied by measuring Mg2+ release in response to 0.5 and 20 microM phenylephrine. During preperfusion exogenous Mg2+ was added to the medium to give 1.2 mM. 5 min before starting the addition of phenylephrine the infusion of exogenous Mg2+ was stopped. Mg2+ in the perfusate leaving the liver was measured by atomic absorption spectroscopy. Analysis of the Mg2+ decay curves with two exponential models indicated that phenylephrine caused dose-dependent Mg2+ release from perfused rat livers. |
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Authors:
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A Jakob; J Becker; G Schöttli; G Fritzsch |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: FEBS letters Volume: 246 ISSN: 0014-5793 ISO Abbreviation: FEBS Lett. Publication Date: 1989 Mar |
Date Detail:
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Created Date: 1989-06-08 Completed Date: 1989-06-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0155157 Medline TA: FEBS Lett Country: NETHERLANDS |
Other Details:
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Languages: eng Pagination: 127-30 Citation Subset: IM |
Affiliation:
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Department of Biochemistry, Vesalianum, University of Basel, Switzerland. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Glucose / metabolism Glycogen / metabolism Kinetics Liver / drug effects, metabolism* Magnesium / metabolism* Male Phenylephrine / pharmacology* Rats Receptors, Adrenergic, alpha / drug effects, physiology* Spectrophotometry, Atomic |
| Chemical | |
Reg. No./Substance:
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0/Receptors, Adrenergic, alpha; 50-99-7/Glucose; 59-42-7/Phenylephrine; 7439-95-4/Magnesium; 9005-79-2/Glycogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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