Document Detail


Alopecia totalis: is treating nonresponder patients useful?
MedLine Citation:
PMID:  2061445     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to assess the effectiveness of different treatments in patients with alopecia totalis or universalis who did not respond to sensitizing therapies. Twenty-six patients, who had been receiving sensitizing therapy for at least 1 year without any response, were randomly assigned to receive the following treatments: topical 10% cyclosporine in oily solution (eight patients), PUVA (eight patients), and intravenous thymopentin (ten patients). None of them had any acceptable regrowth after at least 6 months of treatment. Our results suggest that other treatments are not useful in patients with 100% hair loss who fail to respond to sensitizing therapies.
Authors:
A Tosti; F Bardazzi; L Guerra
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Publication Detail:
Type:  Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial    
Journal Detail:
Title:  Journal of the American Academy of Dermatology     Volume:  24     ISSN:  0190-9622     ISO Abbreviation:  J. Am. Acad. Dermatol.     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-08-06     Completed Date:  1991-08-06     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7907132     Medline TA:  J Am Acad Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  455-6     Citation Subset:  IM    
Affiliation:
Department of Dermatology, University of Bologna, Italy.
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Adolescent
Adult
Aged
Alopecia / drug therapy,  therapy*
Cyclosporins / administration & dosage
Female
Humans
Injections, Intravenous
Male
Middle Aged
Photochemotherapy
Random Allocation
Thymopentin / administration & dosage
Chemical
Reg. No./Substance:
0/Cyclosporins; 69558-55-0/Thymopentin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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