Document Detail

Alopecia in congenital hidrotic ectodermal dysplasia responding to treatment with a combination of topical minoxidil and tretinoin.
MedLine Citation:
PMID:  19200200     Owner:  NLM     Status:  MEDLINE    
Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis. Alopecia is due to decrease in number and degree of maturation of the hair follicles. Tretinoin is a mitogen by itself and also enhances the absorption of minoxidil which acts by enlarging the miniaturized hair follicles. We report a case of alopecia in Clouston's syndrome who responded to treatment with topical minoxidil and tretinoin.
Shubha Melkote; Rachita S Dhurat; Anjali Palav; Hemangi R Jerajani
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  48     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  184-5     Citation Subset:  IM    
Department of Dermatology, LTM Medical College and General Hospital, Sion, Mumbai, India.
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MeSH Terms
Administration, Topical
Alopecia / drug therapy*,  etiology*
Dermatologic Agents / administration & dosage
Drug Therapy, Combination
Ectodermal Dysplasia / complications*
Hair / drug effects,  growth & development
Minoxidil / administration & dosage*
Tretinoin / administration & dosage*
Reg. No./Substance:
0/Dermatologic Agents; 302-79-4/Tretinoin; 38304-91-5/Minoxidil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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