Document Detail


Alopecia in congenital hidrotic ectodermal dysplasia responding to treatment with a combination of topical minoxidil and tretinoin.
MedLine Citation:
PMID:  19200200     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis. Alopecia is due to decrease in number and degree of maturation of the hair follicles. Tretinoin is a mitogen by itself and also enhances the absorption of minoxidil which acts by enlarging the miniaturized hair follicles. We report a case of alopecia in Clouston's syndrome who responded to treatment with topical minoxidil and tretinoin.
Authors:
Shubha Melkote; Rachita S Dhurat; Anjali Palav; Hemangi R Jerajani
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of dermatology     Volume:  48     ISSN:  1365-4632     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2009 Feb 
Date Detail:
Created Date:  2009-02-09     Completed Date:  2009-06-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  184-5     Citation Subset:  IM    
Affiliation:
Department of Dermatology, LTM Medical College and General Hospital, Sion, Mumbai, India. shubha_melkote@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Administration, Topical
Alopecia / drug therapy*,  etiology*
Child
Dermatologic Agents / administration & dosage
Drug Therapy, Combination
Ectodermal Dysplasia / complications*
Hair / drug effects,  growth & development
Humans
Male
Minoxidil / administration & dosage*
Tretinoin / administration & dosage*
Chemical
Reg. No./Substance:
0/Dermatologic Agents; 302-79-4/Tretinoin; 38304-91-5/Minoxidil

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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