Document Detail


Almond allergens: molecular characterization, detection and clinical relevance.
MedLine Citation:
PMID:  22260748     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Almond (Prunus dulcis) has been widely used in all sorts of food products (bakery, pastry, snacks) mostly due to its pleasant flavor and to its health benefits. However, it is also classified as a potential allergenic seed known to be responsible for triggering several mild to life-threatening immune reactions in sensitized and allergic individuals. Presently, eight groups of allergenic proteins have been identified and characterized in almond, namely PR-10 (Pru du 1), TLP (Pru du 2), prolamins (Pru du 2S albumin, Pru du 3), profilins (Pru du 4), 60sRP (Pru du 5) and cupin (Pru du 6, Pru du -conglutin), although only few of them have been tested for reactivity with almond-allergic sera. To protect sensitized individuals, labeling regulations have been implemented for foods containing potential allergenic ingredients, impelling the development of adequate analytical methods. This work aims to present an updated and critical overview about the molecular characterization and clinical relevance of almond allergens, as well as revising the main methodologies used to detect and quantitate food allergens with special emphasis to almond.
Authors:
Joana Costa; Isabel Mafra; Isabel Carrapatoso; M Beatriz P P Oliveira
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-20
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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