Document Detail

Allylestrenol: three years of experience with Gestanon in threatened abortion and premature labor.
MedLine Citation:
PMID:  7459930     Owner:  NLM     Status:  MEDLINE    
Allylestrenol was used to treat 375 women with threatened pregnancies. Results show that this drug is capable of maintaining pregnancy in a large series of ambulant patients and is safe for both mother and child. Allylestrenol does not maintain pregnancy if placental dysfunction is present, however. Newborns whose mothers are treated with allylestrenol have slightly higher birth weights than controls. The possible role of allylestrenol in this process is discussed. At high doses, allylestrenol effectively stops premature labor, suggesting a selective action on the myometrium.
J Cortés-Prieto; A O Bosch; J A Rocha
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical therapeutics     Volume:  3     ISSN:  0149-2918     ISO Abbreviation:  Clin Ther     Publication Date:  1980  
Date Detail:
Created Date:  1981-04-24     Completed Date:  1981-04-24     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  7706726     Medline TA:  Clin Ther     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  200-8     Citation Subset:  IM    
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MeSH Terms
Abortion, Threatened / drug therapy*
Allylestrenol / therapeutic use*
Estrenes / therapeutic use*
Estrogens / urine
Obstetric Labor, Premature / drug therapy*
Placenta / pathology
Reg. No./Substance:
0/Estrenes; 0/Estrogens; 432-60-0/Allylestrenol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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