Document Detail

Allosteric regulation of the conformational dynamics of a cavitand receptor.
MedLine Citation:
PMID:  16898795     Owner:  NLM     Status:  PubMed-not-MEDLINE    
[reaction: see text] Inspired by allostery in nature, we synthesized cavitand 1 and investigated regulation of its conformational dynamics. Quantitative 1H NMR studies have revealed that the rate of the conformational isomerization of 1 can be modulated using the external addition of acid. As 1 maintains its vase-like conformation in an acidic environment, ample opportunities for controlling the kinetics of molecular recognition, and thus reactivity, in this and related receptors have arisen.
Zhiqing Yan; Yuning Chang; Dennis Mayo; Veselin Maslak; Shijing Xia; Jovica D Badjić
Related Documents :
9778315 - Reactions of n-methyl-2-phenylindole with malondialdehyde and 4-hydroxyalkenals. mechan...
15468105 - Photoelectron resonance capture ionization mass spectrometry: a soft ionization source ...
1855885 - Alkylating potency of nitrosated amino acids and peptides.
409465 - Polymers of biogenic amines.
22104435 - Design, synthesis, and biological evaluation of novel (1-thioxo-1,2,3,4-tetrahydro-β-c...
8552205 - In vitro antileukemic activity and chemical transformation of the 5'-chloro-5'-deoxy de...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Organic letters     Volume:  8     ISSN:  1523-7060     ISO Abbreviation:  Org. Lett.     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-08-10     Completed Date:  2007-06-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3697-700     Citation Subset:  -    
Department of Chemistry, The Ohio State University, 100 West 18th Avenue, Columbus, Ohio 43210, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  1,6-Stannatropic strategy: effective generation and cyclization of 1,5-dipoles from o-stannylmethyla...
Next Document:  Facile synthesis of complicated 9,9-diarylfluorenes based on BF3.Et2O-mediated Friedel-Crafts reacti...