Document Detail


Allogeneic bone marrow transplant for refractory mediastinal germ cell tumour: possible evidence of graft-versus-tumour effect.
MedLine Citation:
PMID:  17229257     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Mediastinal germ cell tumours (GCT) carry a poor prognosis, particularly after relapse. We have reviewed the published reports of current treatments and describe a case with a cure after an allogeneic bone marrow transplant, which is not reported in the current published data. We believe that GCT may be susceptible to a graft-versus-tumour effect and suggest that patients with relapsed GCT be considered for allogeneic transplantation.
Authors:
A Goodwin; H Gurney; D Gottlieb
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Internal medicine journal     Volume:  37     ISSN:  1445-5994     ISO Abbreviation:  Intern Med J     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-18     Completed Date:  2007-03-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101092952     Medline TA:  Intern Med J     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  127-9     Citation Subset:  IM    
Affiliation:
Westmead Hospital Medical Oncology Department, Westmead Hospital, Westmead, NSW, Australia. annabeg@westgate.wh.usyd.edu.au
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MeSH Terms
Descriptor/Qualifier:
Adult
Bone Marrow Transplantation / methods*
Graft vs Tumor Effect*
Humans
Male
Mediastinal Neoplasms / surgery*
Neoplasm Recurrence, Local / diagnosis,  surgery
Neoplasms, Germ Cell and Embryonal / surgery*
Transplantation, Homologous

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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