Document Detail


Allithiamine ingestion does not enhance isokinetic parameters of muscle performance.
MedLine Citation:
PMID:  9063763     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The purpose of this study was to investigate the effect of oral allithiamine administration on isokinetic parameters of muscle performance and lactate accumulation prior to, during and in recovery from isokinetic exercise. A double-blind, counterbalanced, crossover experimental design utilizing a Biodex System 2 Isokinetic Dynamometer was used to test 15 healthy college students. Subjects orally ingested either 1 g. day-1 of a thiamin derivative, allithiamine, or placebo for 5 days and then performed six exercise sets of knee extension and flexion. ANOVA revealed no significant differences between treatment conditions in peak torque, mean peak torque, average power, or total work performed (p > .05). Likewise, lactate accumulation was not significantly different between treatment conditions at any measurement point (p > .05). The absence of significant differences suggests that oral allithiamine administration does not enhance isokinetic parameters of muscle performance or lactate accumulation prior to, during, and following isokinetic exercise.
Authors:
M R Doyle; M J Webster; L D Erdmann
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Publication Detail:
Type:  Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  International journal of sport nutrition     Volume:  7     ISSN:  1050-1606     ISO Abbreviation:  Int J Sport Nutr     Publication Date:  1997 Mar 
Date Detail:
Created Date:  1997-05-13     Completed Date:  1997-05-13     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9307702     Medline TA:  Int J Sport Nutr     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  39-47     Citation Subset:  IM    
Affiliation:
Department of Physical Education, Western Illinois University, Macomb 61455, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Cross-Over Studies
Double-Blind Method
Exercise
Female
Humans
Lactates / blood
Male
Muscle Contraction / drug effects*
Muscle, Skeletal / drug effects*
Thiamine / analogs & derivatives*,  pharmacology
Chemical
Reg. No./Substance:
0/Lactates; 554-44-9/allithiamine; 59-43-8/Thiamine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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