Document Detail

Allergy symptom response to intradermal testing-based immunotherapy: a retrospective study of clinical practice.
MedLine Citation:
PMID:  15365539     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: Evaluate the multiple end-organ targets affected by intradermal testing (IDT)-based immunotherapy. Study design and setting We conducted a retrospective medical record review of 139 patients, as well as a follow-up questionnaire in a university setting. RESULTS: Statistically significant differences (t-tests, P < 0.05) were observed in the prevalence of symptoms after IDT-based immunotherapy for each category (ear, eye, nasal, and throat). When divided into treatment time groups, the reduction was less in the first group (0-6 months therapy), than the subsequent groups (6-24 months and >24 months). The reduction leveled off after 6 months of therapy, with no difference seen between the 6- to 24-month and >24-month groups. CONCLUSIONS: IDT-based immunotherapy has a broad response on otolaryngic allergy symptoms that appears to be consistent over time. SIGNIFICANCE: IDT-based immunotherapy is an effective form of treatment for allergy-induced diseases of the head and neck.
David Rouse; Debra L Park; Thomas Sanford
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery     Volume:  131     ISSN:  0194-5998     ISO Abbreviation:  Otolaryngol Head Neck Surg     Publication Date:  2004 Sep 
Date Detail:
Created Date:  2004-09-14     Completed Date:  2004-10-26     Revised Date:  2009-11-03    
Medline Journal Info:
Nlm Unique ID:  8508176     Medline TA:  Otolaryngol Head Neck Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  220-4     Citation Subset:  IM    
Department of Otolaryngology Head and Neck Surgery, University of Kansas Medical Center, Kansas City, Kansas, USA.
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MeSH Terms
Aged, 80 and over
Follow-Up Studies
Hypersensitivity / diagnosis,  immunology*,  therapy*
Middle Aged
Otorhinolaryngologic Diseases / immunology*,  therapy*
Retrospective Studies
Skin Tests

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