Document Detail


Allergy-preventive effects of the flowers of Impatiens textori.
MedLine Citation:
PMID:  20410612     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The allergy-preventive activity of a 35% EtOH extract (IT) of flowers of Impatiens textori MIQ. was demonstrated in a continuing search for allergy-preventive substances from natural sources. The evaluation of its activity used an in vivo assay method for monitoring the blood flow decrease in the tail vein microcirculation of mice subjected to sensitization with hen-egg white lysozyme. Among the principal compounds in IT, apigenin (1), luteolin (3), and luteolin 7-glucoside (4) showed significant allergy-preventive effects.
Authors:
Emiko Iwaoka; Hisae Oku; Munekazu Iinuma; Kyoko Ishiguro
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Biological & pharmaceutical bulletin     Volume:  33     ISSN:  1347-5215     ISO Abbreviation:  Biol. Pharm. Bull.     Publication Date:  2010  
Date Detail:
Created Date:  2010-04-22     Completed Date:  2010-11-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9311984     Medline TA:  Biol Pharm Bull     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  714-6     Citation Subset:  IM    
Affiliation:
Department of Pharmacy, Hyogo University of Health Sciences, Japan.
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MeSH Terms
Descriptor/Qualifier:
Animals
Anti-Allergic Agents / pharmacology,  therapeutic use*
Apigenin / pharmacology
Chickens
Egg White
Flavones / pharmacology
Flowers
Glucosides / pharmacology*
Hemorheology / drug effects
Hypersensitivity, Delayed / chemically induced,  physiopathology,  prevention & control*
Impatiens / chemistry*
Luteolin / pharmacology
Mice
Muramidase
Phytotherapy
Plant Extracts / pharmacology,  therapeutic use*
Tail / blood supply
Chemical
Reg. No./Substance:
0/Anti-Allergic Agents; 0/Flavones; 0/Glucosides; 0/Plant Extracts; 491-70-3/Luteolin; 520-36-5/Apigenin; EC 3.2.1.17/Muramidase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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