Document Detail

Allergic contact granuloma due to palladium following ear piercing.
MedLine Citation:
PMID:  17101008     Owner:  NLM     Status:  MEDLINE    
Two cases of sarcoidal-type allergic contact granuloma due to metals in ear piercing are presented, the first to palladium (Pd) only, and the second to Pd and possibly also to other metals. Both the patients developed papulonodular lesions at the helices following ear piercing, which after 3-4 weeks, became more granulomatous and very resistant to treatment. Indeed, repeated intralesional injections with corticosteroids produced only a temporary regression of the lesions. Biopsies from the persistent granulomatous lesions from the helices in both the patients and the positive test to Pd in case 2, 3 weeks after the patch-testing procedure, demonstrated epithelioid granulomas, with some multinucleate histiocytes surrounded by a lymphocytic-histiocytic infiltrate. Areas of fibrinoid necrosis were found in both the helix biopsies. An infectious pathology was excluded. Patch testing showed a strong positive reaction to Pd only in case 1 and to Pd and nickel in case 2. Chemical analysis of the earring of patient 1 confirmed the presence of Pd; however, analysis of the earrings of the second patient did not show the presence of Pd, but showed the presence of nickel and copper. Both the clinical and histological findings concur with some rarely reported similar observations in the literature.
An Goossens; Ann De Swerdt; Karen De Coninck; Johan Ernest Snauwaert; Marleen Dedeurwaerder; Marc De Bonte
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  55     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-14     Completed Date:  2007-02-15     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  338-41     Citation Subset:  IM    
Department of Dermatology, University Hospital, K.U. Leuven, Belgium.
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MeSH Terms
Allergens / adverse effects*
Body Piercing / adverse effects*
Dermatitis, Allergic Contact / diagnosis*,  pathology
Diagnosis, Differential
Ear, External / pathology*
Granuloma / diagnosis*,  pathology
Middle Aged
Palladium / adverse effects*
Patch Tests
Reg. No./Substance:
0/Allergens; 7440-05-3/Palladium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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